AB1005 BULLOUS LUPUS (BSLE) AS THE FIRST MANIFESTATION OF SYSTEMIC LUPUS ERYTHEMATOSUS IN THE PEDIATRIC POPULATION (PSLE): A DIAGNOSTIC CHALLENGE IN DAILY PRACTICE
نویسندگان
چکیده
منابع مشابه
Hematologic manifestation of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. The most common hematologic finding is anemia, leukopenia, thrombocytopenia and secondary antiphospholipid syndrome with recurrent abortion and thrombosis. The autoimmune fibrosis of bone marrow is another manifestation of autoimmune disease especially SLE, that must be correctly differentiated from primary myelofibrosis.
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A 22-year-old woman presented to the internal medicine department with a 2 month history of progressive blistering eruption. She also complained of arthralgias and lower limb edema. Physical examination found blisters on her hands (Picture 1) and feet. Skin biopsy showed subepidermal blister with polymorphous inflammatory infiltrate (Picture 2). Direct immunofluorescence demonstrated linear dep...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2020
ISSN: 0003-4967,1468-2060
DOI: 10.1136/annrheumdis-2020-eular.6359